proprotein convertases การใช้

The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products.
First, proprotein convertases cut the precursor at specific sites to generate intermediates containing C-terminal basic residues ( lysine and / or arginine ).
Several proteins within the pathway require either Ca 2 + ions, Mn 2 + ions, or divalent ions to function as aminopeptidase P, Proprotein convertases and sulfotransferases.
As with many proteins, PCSK9 is inactive when first synthesized, because a section of peptide chains blocks their activity; proprotein convertases remove that section to activate the enzyme.
Furin-like proprotein convertases ( PPC ) are responsible for conversion of 50 kDa HJV to a 40 kDa protein with a truncated COOH-terminus, at a conserved polybasic RNRR site.